A new rhythm for digestive health.
Vibrant Gastro is pioneering a different approach to chronic idiopathic constipation: drug-free technology designed to stimulate natural colonic motility through micro-vibrations.
Drug-free device innovation
Not another drug. A different mechanism.
Vibrant Gastro pioneered the Synchronized Activation Method™, the first-in-class drug-free technology behind the Vibrant System™.
Instead of relying on a pharmaceutical ingredient, the system uses micro-vibrations to stimulate the colon mechanically, designed to improve natural colonic motility.
The technology also provides a platform for exploration of future data-driven, personalized treatment approaches involving the gut-brain connection and enteric nervous system. Those potential applications are not the current cleared indication.
Mechanics, not medication.
A new approach to helping the colon do what it is naturally designed to do.
Rethink the mechanism
Chronic constipation demands more options than another conventional drug-based approach.
Use physical stimulation
The vibrating capsule applies mechanical stimulation through the Synchronized Activation Method™.
Keep innovating
Explore how this technology might support future personalized digestive-health solutions.
Our Mission
Create drug-free treatments that enable millions of people to live more enjoyable lives via new products that synchronize and activate the gut-brain connection to provide control over their bodies and predictable symptom relief.
Leadership behind the innovation.
Experience spanning medical technology, research, operations, market access, commercial growth and product development.
Adam Kahn
Chief Executive Officer
Douglas Maley
VP Sales & Marketing
Mark Olmstead
VP Market Access
Martha Bezalel
COO & GM, Israel
Shai Lankry
Chief Financial Officer
Lior Ben Tsur
President & Co-Founder
Shai Molnar
Vice President, R&D
Uri Neria
Head of Product
Informed by leading minds in GI.
Explore the perspectives and backgrounds of physicians and researchers advising Vibrant.
Dr. Satish Rao
MD, PhD, FRCP (LON), FACG, AGAF
- Digestive health expert who helped launch the Augusta University Digestive Health Center.
- Recognized researcher, educator, and master clinician.
- Research spans IBS, constipation, fecal incontinence, and visceral pain.
“The other striking thing was the side effects. Virtually none. ‘Hardly anybody felt this.’ ‘There was no diarrhea.’ The combination of highly efficacious data with very minimal or no side effects is a brilliant package.”
Dr. Eamonn Quigley
MD, Professor of Medicine
- Former editor-in-chief of The American Journal of Gastroenterology and former vice president of the American College of Gastroenterology.
- Author of more than 500 articles, six books, and several monographs.
- Recipient of honors from leading medical and gastroenterological societies.
“[Vibrant] really put the vibrating capsule on the horizon for doctors in terms of a totally novel treatment for constipation.”
Dr. Christine Frissora
MD, Gastroenterologist
- Cornell-trained gastroenterologist and associate professor at Weill Cornell Medicine.
- Has developed and chaired nationally recognized courses focused on irritable bowel syndrome.
- Advocate for women’s GI health through Weill Cornell’s Office of Women in Medicine & Science.
“We think [Vibrant] could be a very good, effective first-line therapy for chronic idiopathic constipation.”
Dr. Anthony Lembo
MD, Professor of Medicine
- Gastroenterologist and Harvard Medical School faculty member.
- Clinical interests include motility disorders, IBS, swallowing disorders, endoscopy, colon cancer screening, and GERD.
- Board-certified in internal medicine and gastroenterology.
Research interests include gastrointestinal motility, IBS and other digestive disorders.
Dr. Darren Brenner
MD, Gastroenterologist
- Professor of Medicine and Surgery at Northwestern University.
- Director of Neurogastromotility and Integrated Bowel Dysfunction programs.
- Author of more than 150 publications and co-author of the first ACG guideline on IBS.
“The patients’ biggest concern is that the medications cause diarrhea, and they can’t titrate these appropriately. That doesn’t seem to be a concern with the vibrating capsule.”
Dr. William Chey
MD, Professor of Medicine
- Professor of gastroenterology at Michigan Medicine, Ann Arbor.
- Research focuses on functional bowel disorders and H. pylori infection.
- Medical innovator and former co-editor-in-chief of The American Journal of Gastroenterology, with more than 350 manuscripts.
“The [vibrating capsule] is both safe and effective in patients with chronic idiopathic constipation. It offers a novel non-medication means by which to treat patients with CIC.”
Dr. Brennan Spiegel
MD, Gastroenterologist
- Director of Health Services Research and Digital Health Ethics Chair at Cedars-Sinai.
- Pioneer in medical extended reality and leader in the field of digital therapeutics.
- Former editor-in-chief of The American Journal of Gastroenterology with more than 270 publications.
“This is very exciting to have an approach that is here to help with the symptoms of constipation and even can improve quality of life from the data that we’re seeing so far and do it in a way that doesn’t lead to diarrhea.”
Advisor comments are reproduced from the existing Vibrant About Us page; opinions expressed in quotations are attributed to the individual physicians.
References and source material
- Satish S.C. Rao et al. Randomized Placebo-Controlled Phase 3 Trial of Vibrating Capsule for Chronic Constipation. Gastroenterology, 164(7), 1202–1210.e6, June 2023.
- Lembo A et al. The colonic biological clock and predictability of time of bowel movements during treatment with a vibrating capsule (Vibrant®) in patients with severe chronic idiopathic constipation. Oral abstract, Digestive Disease Week, May 2023.
- National Institute of Diabetes and Digestive and Kidney Diseases. Symptoms and Causes of Constipation; Eating, Diet, and Nutrition for Constipation; Definition and Facts for Constipation.
- Bassotti G et al. Chronic Idiopathic Constipation in Adults: A Review on Current Guidelines and Emerging Treatment Options. Clinical and Experimental Gastroenterology, 2021;14:413–428.
- Quigley EMM et al. Better Understanding and Recognition of the Disconnects, Experiences, and Needs of Patients with Irritable Bowel Syndrome with Constipation (BURDEN IBS-C) Study. Advances in Therapy, 2018;35:967–980.
*CIC = chronic idiopathic constipation. This page is company information, not personalized medical advice. For full indication, safety information, and treatment instructions, consult the current Vibrant System Instructions for Use.