For patients struggling with constipation*,
more movements means more living.
The Vibrant System™ is a first-in-class, FDA-Cleared Capsule Therapy for Chronic Idiopathic Constipation. Clinically proven to deliver effective relief from constipation* with fewer side effects than the most common drugs & laxatives.
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AJGThe American Journal of Gastroenterology
THE LANCET
nature
The New England Journal of Medicine
AMERICAN COLLEGE OF GASTROENTEROLOGY
Advancing Gastroenterology, Improving Patient Care
Gastroenterology
Two-thirds are frustrated with their constipation*
treatment options
Doctors say:
21% Satisfied
79% Unsatisfied
"A survey of 100 high-volume gastroenterology providers found 74 percent don't think the most common medications they prescribe for patients with chronic constipation are working."
— National GI Survey
Patients say:
37% Satisfied
63% Unsatisfied
"I love the fact that it's not another drug. I've eaten handfuls of laxatives & drank every nasty liquid solution there is — without success… With Vibrant, I now have bowel movements 3 — sometimes 4 — times each week. My stomach is not as distended; I've lost 20 pounds & I feel like a normal human being again."
— Cherie F., Chicago
Independent BURDEN-CIC study5
"I feel like a normal human being again"
★★★★★
Cherie F, Chicago, patient with yearslong
chronic constipation
Read More
chronic constipation
For Healthcare Professionals
Market Access
Market Access
and Reimbursement
Professional resources for coverage, coding, prior authorization, and payer information for the Vibrant System™.
Clinical Evidence
Peer-reviewed publications supporting the Vibrant System™ — from the pivotal Phase 3 RCT through real-world long-term outcomes.
2023
Gastroenterology · June 2023
Randomized Placebo-Controlled Phase 3 Trial of Vibrating Capsule for Chronic Constipation
Pivotal Phase 3 RCT establishing the foundation for FDA clearance.
2024
Alimentary Pharmacology & Therapeutics · Aug 9, 2024
Effects of Treatment with a Vibrating Capsule in Patients with Severe Chronic Constipation
Post hoc analysis of pivotal study in severe CIC patients.
2024
Advances in Therapy · Nov 11, 2024
Cost-Effectiveness of Vibrant System vs. Linaclotide in Chronic Idiopathic Constipation
Health-economic modeling versus a leading prescription comparator.
2025
Neurogastroenterology & Motility · Mar 10, 2025
The Vibrating Capsule: Safety and Tolerability in Patients with Chronic Idiopathic Constipation
Safety and tolerability profile across the CIC population.
2025
Clinical and Translational Gastroenterology · Nov 2025
Real-World Evidence of the Long-Term Clinical Utility of a Vibrating Capsule in the Management of Chronic Idiopathic Constipation
1,722 patients analyzed; 491 and 298 completed 3- and 6-month follow-up respectively.
* Chronic Idiopathic Constipation (CIC) in adults.
5. Independent BURDEN-CIC study — patient and physician satisfaction with current CIC treatment options.
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