Clinically proven to deliver lasting, effective relief from chronic idiopathic constipation (CIC) with fewer nasty side effects than drugs and laxatives, the Vibrant® system can provide safe, predictable relief for patients with CIC.
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Vibrant® System – Information for Patients
What Is the Vibrant System — and Who Should Use It?
The Vibrant System is an orally administered capsule therapy indicated for adults with chronic idiopathic constipation (CIC) who have not found relief with laxatives at recommended dosages for at least one month.
CIC is typically associated with:
- Straining during bowel movements
- Lumpy or hard stools
- A feeling of incomplete evacuation
- Sensation of blockage while on the toilet
- Three or fewer bowel movements per week, often requiring manual assistance
The kit includes a reusable Pod (charger/activator), USB cable & adapter, and single-use Vibrant Capsules.
Who Should Not Use the Vibrant System?
Avoid use if you:
- Have a history of obstructive or complicated diverticular disease
- Have known or suspected bowel obstruction
- Currently experience significant gastroparesis
- Have inflammatory bowel disease, GI malignancy, Zenker’s diverticulum, severe swallowing disorders, or achalasia
- Are pregnant or breastfeeding
Important Safety Information
Warnings
- Do not undergo MRI while a capsule may still be in your body. Confirm passage via abdominal X-ray if needed.
- Keep capsules away from pacemakers, defibrillators, or other implants that could be affected by a magnetic field.
- Never swallow a capsule that hasn’t been activated in the Pod.
- Store capsules out of reach of children; seek immediate help if accidentally ingested by a child.
Precautions
- Do not use if packaging is damaged or the capsule is past its expiration date.
- Long-term use beyond 8 weeks has not yet been evaluated; your clinician should reassess ongoing need.
Expected Benefits & Potential Risks
In a pivotal study, 40 % of Vibrant users achieved at least one additional complete bowel movement per week versus 22 % with placebo, with improvements in quality of life, straining, and stool consistency.
Possible side-effects include abdominal pain, bloating, nausea, vomiting, diarrhea, blood in stool, gas, or rare bowel obstruction.
How to Use the Vibrant System
Setting Up the Pod
- Plug the USB cable into the Pod and AC adapter, then into a wall outlet.
- The light ring flashes, then turns solid blue — Pod is ready.
Activating & Taking a Capsule
- Remove a capsule from its blister pack.
- Place it in the Pod groove; wait for the light to turn solid green and an audible beep.
- Swallow immediately with ~8 oz water.
- Take capsules on a schedule of 3 days on, 1 off, 2 on, 1 off, ideally right before bedtime.
Storage & Maintenance
Pod: Keep dry, out of direct sunlight; wipe with 70 % isopropyl alcohol before first and each subsequent use.
Capsules: Store below 77 °F / 25 °C in original blister, away from magnets and sunlight.
Symbols
This device is prescription-only, single-use for the capsule, and includes standard dry-keep and Type BF applied-part symbols.
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“I feel like a normal human being again!”
- Cherie F, Chicago, a patient with longtime chronic constipation
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“I love the fact that it’s not another drug. I’ve eaten handfuls of laxatives & drank every nasty liquid solution there is – without success… With Vibrant, I now have bowel movements 3 – sometimes 4 – times each week. My stomach is not as distended; I’ve lost at least 20 pounds, & I feel like a normal human being again.”— Cherie F., a patient from Chicago
A different kind of constipation relief, designed to make a real difference
More predictable bowel movements
More frequent bowel movements
Fewer unpleasant side effects
Straining & Bloating Aren't Forever.
Vibrant is a drug-free capsule that effectively treats constipation (CIC) without the nasty side-effects of laxatives and drugs.
People are frustrated with their current treatment options.
Millions of people are suffering in silence, trying as many things as they can, but not making progress. Over 60% say current treatments, which often cause diarrhea, are worse than the constipation itself. Just 1.2% of those using the Vibrant capsule reported diarrhea.
Get Vibrant from your clinician
Find a clinician who can help
Manage Your Vibrant System Treatment in the App.
Reminders, Tracking & Better Results
The App Features:
✓ E-Diary ✓ Progress Reports ✓ Reminders & Tips
Our Team Loves to Help!
Our VibrantConnect team can help answer your questions about trying Vibrant, finding a clinician nearby, coverage, how Vibrant works, what to expect, and anything else you may need. We can be helpful in minutes.